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When you inject it or spray it into your mouth, inject it very slowly

Interestingly, another mechanism was proposed as an alternative way to stabilize NRF2 through the interaction between the autophagy adaptor protein p62/sequestosome-1 (p62/SQSTM1) and KEAP1, which leads to the sequestration of KEAP1 in the autophagy-deficient cells and enables NRF2 accumulation [20]

2008 Dec;18(4):273-86

de Klerk N, Maudsdotter L, Gebreegziabher H, Saroj SD, Eriksson B, Eriksson OS, Roos S, Lindn S, Sjlinder H, Jonsson A-B (2016) Lactobacilli reduce Helicobacter pylori attachment to host gastric epithelial cells byinhibiting adhesion gene expression